Patent · US Active

ATF5 peptide variants and uses thereof

US12208131B2 · kind B2 · utility

0Cited by

0References

8Claims

0Family size

Assignee

Sapience Therapeutics, Inc. · DE

Inventors

Barry Jay Kappel · Pelham, US
Gene Merutka · Hillsborough, US
Jimmy Andrew Rotolo · New York, US

Key dates

Filing date	Dec 9, 2023
Grant date	Jan 28, 2025
Priority date	—
Expiry date	Dec 9, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/73
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are ATF5 peptides having a truncated ATF5 leucine zipper region and, optionally, a cell-penetrating region, compositions comprising the ATF5 peptides, and methods of inhibiting proliferation of and promoting cytotoxicity in a neoplastic cell using the ATF5 peptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.