Systems and methods for non-destructive isolation, concentration, and detection for unbiased characterization of nano- and bioparticles
US12208400B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 25, 2022 |
| Grant date | Jan 28, 2025 |
| Priority date | — |
| Expiry date | May 25, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB03C2201/26
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present disclosure provides systems and methods for separating one or more analytes within a fluid mixture, and characterizing and/or detecting properties associated with the one or more analytes. In some embodiments, the systems provided herein contain a dielectrophoresis device, such as a gradient insulator-based dielectrophoresis device (g-iDEP). The present disclosure provides systems and methods for separating and characterizing analytes using particle or nanoparticle tracking analysis (NTA). NTA offers various advantages because, particle size and concentration can be calculated in real time, allowing label-free and simultaneous characterization and separation of samples with mixed and unknown analytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.