Patent · US Active

RET inhibitors, pharmaceutical compositions and uses thereof

US12209085B2 · kind B2 · utility

0Cited by
6References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 6, 2019
Grant dateJan 28, 2025
Priority date
Expiry dateMay 5, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A RET inhibitor, a pharmaceutical composition thereof and uses thereof including a compound having Formula (I) or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof. Furthermore, a pharmaceutical composition including the compound, and uses of the compound and pharmaceutical composition thereof in the manufacture of a medicament for treatment and prevention of RET-related diseases and conditions, including cancer, irritable bowel syndrome, and/or pain associated with irritable bowel syndrome.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.