Versatile peptide and protein macrocyclization and multimerization with diels-alder cycloadditions
US12209143B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Apr 9, 2020 |
| Grant date | Jan 28, 2025 |
| Priority date | — |
| Expiry date | Aug 14, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides macrocyclic and macrobicyclic peptides with secondary structures that are stabilized over the corresponding non-cyclic peptides. The macrocyclic and macrobicyclic peptides are formed from peptides with adduct-forming, complementary reactive side chain moieties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.