Patent · US Active

Bis-octahydrophenanthrene carboxamide derivatives and protein conjugates thereof for use as LXR agonists

US12209180B2 · kind B2 · utility

0Cited by

1References

45Claims

0Family size

Assignee

REGENERON PHARMACEUTICALS, INC. · US

Inventors

Jesper Gromada · Scarsdale, US
Viktoria Gusarova · Pleasantville, US
Amy Han · Hockessin, US
Sokol Haxhinasto · Brookfield, US
Andrew J. Murphy · Croton-on-Hudson, US
William Olson · Ossining, US
Matthew Sleeman · Pidley, GB

Key dates

Filing date	Nov 19, 2019
Grant date	Jan 28, 2025
Priority date	—
Expiry date	Feb 23, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/26
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are compounds or payloads, linker-payloads, antibody-drug conjugates, and compositions, and methods for the treatment of diseases and disorders associated with the liver X receptor, including bis-octahydrophenanthrene carboxamides and protein (e.g., antibody) drug conjugates thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.