Methods and compositions for treating melanoma

US12213977B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Thomas G. Graeber · Los Angeles, US
• Jennifer Tsoi · Los Angeles, US
• Antoni Ribas · Los Angeles, US
• Lidia Robert · Los Angeles, US
• Nicolaos Palaskas · Los Angeles, US

Key dates

• Filing date: Jun 27, 2018
• Grant date: Feb 4, 2025
• Expiry date: Jan 20, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K45/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The current methods and compositions provide for a novel therapeutic method for treating patients diagnosed with melanoma, especially those that have become resistant to certain other therapies. Accordingly, certain aspects of the disclosure relate to a method for treating melanoma in a subject, the method comprising administering a composition comprising a ferroptosis-inducing agent or other dedifferentiated melanoma-targeting agent to the subject.