Patent · US Active

Antigen binding molecule formats

US12215148B2 · kind B2 · utility

1Cited by

1References

25Claims

0Family size

Assignee

REGENERON PHARMACEUTICALS, INC. · US

Inventors

Tong Zhang · Beijing, CN
Erica Pyles · New City, US
Michael Rosconi · New City, US
Nina Liu · Chappaqua, US
Supriya Patel · Mamaroneck, US
Eric Smith · New York, US
Andrew J. Murphy · Croton-on-Hudson, US
Chiayang Lin · Scarsdale, US
Samuel Davis · New York, US

Key dates

Filing date	Aug 7, 2020
Grant date	Feb 4, 2025
Priority date	—
Expiry date	Aug 25, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.