Patent · US Active

Integrative DNA and RNA library preparations and uses thereof

US12215314B2 · kind B2 · utility

0Cited by
7References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 26, 2019
Grant dateFeb 4, 2025
Priority date—
Expiry dateNov 20, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6806
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention relates to integrated DNA and RNA library preparations and methods of making and uses thereof, wherein the DNA molecules are labelled with a tag identifying the molecule as being a DNA molecule and the RNA molecules are labelled with a tag identifying the molecule as being a RNA molecule. The methods do not require physical separation of DNA and RNA. The methods output two separate libraries from DNA and RNA, respectively, which helps flexible manipulation on downstream sequencing platforms. The application also claims the DNA library and the cDNA library produced by the method and the DNA tag and the RNA tag used in the method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.