Compositions and methods for gene editing by targeting transferrin
US12215320B2 · kind B2 · utility
0Cited by
0References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jan 11, 2019 |
| Grant date | Feb 4, 2025 |
| Priority date | — |
| Expiry date | Mar 22, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided include compositions, methods, and systems for modulating the expression, function, and/or activity of a target gene, for example a blood-clotting protein such as Factor VIII (FVIII), in a cell by genome editing. Also provided include compositions, methods, and systems for treating a subject having or suspected of having a disorder or health condition, e.g., Hemophilia A, employing ex vivo and/or in vivo genome editing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.