Highly loaded metal oxide materials by self-assembly for extended biologically active molecule release in medical and dental applications
US12220467B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Aug 31, 2021 |
| Grant date | Feb 11, 2025 |
| Priority date | — |
| Expiry date | Jun 28, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L2203/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.