Patent · US Active

Manganese-doped hollow mesoporous silica nanoparticles loaded with curcumin

US12220489B1 · kind B1 · utility

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Key dates

Filing dateJul 3, 2024
Grant dateFeb 11, 2025
Priority date
Expiry dateJul 3, 2044

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Manganese-doped hollow mesoporous silica nanoparticles loaded with curcumin and an application in periodontal bone tissue repair are provided in the present disclosure, belonging to the technical field of targeted delivery of nanoparticles and bone tissue regeneration. In the present disclosure, alendronate is grafted on the surface of silica nanoparticles to achieve bone targeting, manganese is doped on the nanoparticles by a chemical method, and curcumin is wrapped in the nanoparticles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.