Manganese-doped hollow mesoporous silica nanoparticles loaded with curcumin
US12220489B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 3, 2024 |
| Grant date | Feb 11, 2025 |
| Priority date | — |
| Expiry date | Jul 3, 2044 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Manganese-doped hollow mesoporous silica nanoparticles loaded with curcumin and an application in periodontal bone tissue repair are provided in the present disclosure, belonging to the technical field of targeted delivery of nanoparticles and bone tissue regeneration. In the present disclosure, alendronate is grafted on the surface of silica nanoparticles to achieve bone targeting, manganese is doped on the nanoparticles by a chemical method, and curcumin is wrapped in the nanoparticles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.