Solid-phase extraction material, and preparation method and use thereof

US12220685B2 · kind B2 · utility

Assignee

• Nanjing University · CN

Inventors

• Qing Zhou · Tangxia, CN
• Ziang Zhang · Trondheim, NO
• Junxia Chen · Nanjing, CN
• Yurong Chen · Beijing, CN
• Chongtian Lei · Nanjing, CN
• Ranqiu Wang · Nanjing, CN
• Weiwei Zhou · Nanjing, CN
• Libin Zhang · Changzhou City, CN

Key dates

• Filing date: May 6, 2022
• Grant date: Feb 11, 2025
• Expiry date: May 6, 2042

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P10/20
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The present invention relates to the field of solid-phase extraction, and particularly to a solid-phase extraction material, and a preparation method and use thereof. The preparation method includes prepolymerizing the monomers N-vinylpyrrolidone and divinylbenzene in the presence of a chain transfer agent, adding prepolymer dropwise to an emulsion of monodispersed seed microspheres, swelling, and reacting to prepare white spheres; and functionalizing the white spheres, to obtain the solid-phase extraction material. The solid-phase extraction material prepared by the reaction has good spherical morphology, large specific surface area, and high ion exchange capacity. The prepared solid-phase extraction material functions in the separation and enrichment of PPCPs by means of a variety of forces with a high extraction rate. The extraction rate is basically maintained between 85% and 105%, and acidic, alkaline, neutral and amphoteric substances is capable of being selectively separated.