Signaling and antigen-presenting bifunctional receptors (SABR)
US12221465B2 · kind B2 · utility
0Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 5, 2018 |
| Grant date | Feb 11, 2025 |
| Priority date | — |
| Expiry date | Dec 10, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/7051
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compositions and methods for signaling and antigen-presenting bifunctional receptors (SABRs) comprising one or more antigen presenting domains; and one or more signal transduction domains, wherein the one or more antigen presenting domains comprise a binding fragment of a major histocompatibility complex (MHC) molecule. Various immunological functions of the SABRs are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.