Bioactive coating material
US12221620B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 15, 2016 |
| Grant date | Feb 11, 2025 |
| Priority date | — |
| Expiry date | Jun 15, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2539/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention refers to a bioactive coating material for coating plastic materials for cell cultures, comprising a polymer conjugate of each a polymer anchor molecule having surface active anchoring groups and one or more biologically active molecules. The anchor molecule is an amphiphilic molecule with a hydrophobic moiety of styrene-, methacrylic acid-, isobutene-, acrylic acid-, acrylic acid ester-, or methacrylic acid ester units and a hydrophilic moiety of units including carboxyl-, amino-, epoxide-, thiol-, alkine- or azide groups. By selecting cell instructive coating materials cell destiny choices are individually and effectively controllable, in particular, the cell adhesion of almost any cell culture one-way articles by the user. With this concept, new options open up for high-throughput-diagnostics, stem cell-biotechnology and regenerative therapies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.