Patent · US Active

Modified pluripotent cells

US12221622B2 · kind B2 · utility

0Cited by

12References

70Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Sonja Schrepfer · San Mateo, US
Tobias Deuse · Hamburg, DE

Key dates

Filing date	May 9, 2020
Grant date	Feb 11, 2025
Priority date	—
Expiry date	May 23, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2800/80
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention discloses for the first time pluripotent cells, including induced pluripotent stem cells, embryonic stem cells, hypo-immune pluripotent cells, cells that have been derived therefrom, and cells that have been biologically differentiated therefrom into particular tissue lineages that are ABO blood type O Rhesus Factor negative or otherwise evade rejection resulting from blood type antigen mismatch. The invention further provides universally acceptable “off-the-shelf” pluripotent cells and derivatives thereof for generating or regenerating specific tissues and organs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.