Substrates for covalent tethering of proteins to functional groups or solid surfaces
US12221648B2 · kind B2 · utility
0Cited by
27References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 13, 2021 |
| Grant date | Feb 11, 2025 |
| Priority date | — |
| Expiry date | May 27, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/54353
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides haloalkane substrates, and linkers for connecting such substrates to functional elements (e.g., tags, labels, surfaces, etc.). Substrates and linkers described herein find use, for example, in labeling, detection, and immobilization of proteins, cells, and molecules. In particular, the linkers provided herein find use within substrates for dehalogenase variants that form covalent bonds with their haloalkane substrates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.