Electrical impedance monitoring device, system and method for locomotion behaviors of Caenorhabditis elegans
US12222305B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 6, 2024 |
| Grant date | Feb 11, 2025 |
| Priority date | — |
| Expiry date | Feb 6, 2044 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH05K2201/10977
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are an electrical impedance monitoring device, system and method for locomotion behaviors of C. elegans. A microfluidic channel layer and a gas channel layer form a double-layer structure by bonding, and the double-layer structure is tightly fixed to a circuit board with nylon screws. An electrode array configured as a concentric circle structure is arranged on the circuit board and used for realizing EIT monitoring of C. elegans. The microfluidic channel layer comprises a culture and monitoring chamber and a C. elegans transition channel and used for long-term culture and cyclic monitoring of C. elegans. The gas channel layer comprises a gas inlet and a gas channel and used for applying a gas pressure to squeeze an upper wall of the microfluidic channel layer to form a membrane valve to close the microfluidic channel layer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.