Patent · US Active

Therapeutic antibodies against ROR-1 protein and methods for use of same

US12222355B2 · kind B2 · utility

0Cited by
196References
9Claims
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Key dates

Filing dateNov 22, 2022
Grant dateFeb 11, 2025
Priority date
Expiry dateJul 31, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Therapeutic antibodies having binding specificity for ROR-1 expressed on cancer cells (particularly leukemic and lymphomic cells) and pharmaceutical compositions containing one or more such antibodies for use in treating cancer. Methods for diagnosing such cancers through in vitro detection of binding to ROR-1 protein expressed on putative cancer cells are also provided.

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