Perfusion loop assembly for an ex-vivo liver perfusion and a method for ex-vivo liver perfusion
US12225900B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 18, 2019 |
| Grant date | Feb 18, 2025 |
| Priority date | — |
| Expiry date | Jun 23, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01N1/126
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
A perfusion loop assembly for ex vivo liver perfusion includes a pump providing perfusion fluid through a line branching at a branching point into a first branch line and a second branch line. The first branch line provides a first portion of the perfusion fluid to the hepatic artery of the liver, the first branch line coupled with a gas exchanger, where the first branch line includes a flow rate sensor and/or a pressure sensor. The second branch line provides a second portion of the perfusion fluid to the portal vein of the liver; the second branch line includes a valve for controlling flow of perfusion fluid into the portal vein. The second branch line includes a flow rate sensor and/or a pressure sensor. A liver chamber assembly holds the liver ex vivo, and an outlet line for the perfusion fluid connects the liver chamber assembly and the pump.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.