Highly sustainable compositions for modulation of gene expression in human skin, and methods of production thereof
US12226379B2 · kind B2 · utility
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Key dates
| Filing date | Feb 8, 2023 |
| Grant date | Feb 18, 2025 |
| Priority date | — |
| Expiry date | Feb 8, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/56
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Formulations containing biologically-produced, high-purity R-mevalonolactone are provided for modulating the expression of genes and metabolism related to epidermal turnover, hyaluronic acid synthesis, barrier function, anti-aging elasticity, extracellular matrix degradation, inflammation, stress, and pigmentation in human skin. The biologically-produced, high-purity R-mevalonolactone may be used as an ingredient in pharmaceutical, food, or cosmetic products and may be applied topically or ingested for modulation of gene expression and metabolism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.