Polyion complex polypeptide hydrogels and uses thereof
US12226546B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 27, 2018 |
| Grant date | Feb 18, 2025 |
| Priority date | — |
| Expiry date | Sep 27, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compositions comprising at least two diblock copolypeptides, wherein each copolypeptide has an ionic segment with the opposite charge from the other. The copolypeptides form β-sheet structured hydrogel assemblies via polyion complexation when mixed in aqueous media. As a result of their unique physical properties, the hydrogels are useful as cell suspension or cell culture media, in drug or cell delivery systems, in scaffolds for tissue repair, or as 3d-printable media.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.