Patent · US Active

Dihydropyridines for the treatment of cognitive impairment or traumatic brain injury

US12227479B2 · kind B2 · utility

0Cited by

2References

19Claims

0Family size

Assignees

United States Government as represented by the Department of Veterans Affairs · US
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · US

Inventors

Michael Ohlmeyer · Plainsboro, US
Dongming Cai · Los Alamos, US

Key dates

Filing date	Oct 10, 2022
Grant date	Feb 18, 2025
Priority date	—
Expiry date	Oct 10, 2042

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A genus of dihydropyridine chemical modulators of synaptojanin is disclosed. These modulators are selective inhibitors of synaptojanin 1 and may be used to treat cognitive impairment or traumatic brain injury, including promoting regeneration in cases of traumatic brain injury, or for treating neurodegenerative disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.