Patent · US Active

Bicyclic compounds as kinase modulators, methods and uses thereof

US12227511B2 · kind B2 · utility

0Cited by
1References
20Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMay 8, 2023
Grant dateFeb 18, 2025
Priority date
Expiry dateMay 18, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D451/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure relates to derivatives of bicyclic compounds and their uses in therapy. In particular, the present disclosure relates to derivatives of bicyclic compounds for use in modulating kinase enzymatic activity and accordingly modulating kinase-dependent diseases and conditions such as cancer and in specific embodiments, hepatocellular carcinoma (HCC). The present disclosure also relates to methods of synthesizing these compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.