Patent · US Active

Bispecific antibody targeting IL-1R1 and NLPR3

US12227579B2 · kind B2 · utility

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12Claims
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Assignee

Inventor

Key dates

Filing dateSep 16, 2019
Grant dateFeb 18, 2025
Priority date
Expiry dateMar 17, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/77
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure concerns modulators of the NLRP3 inflammasome pathway, in particular an NLRP3 inflammasome modulator which is capable of binding to both of IL-1R1 and NLRP3, for use in the treatment or prophylaxis of inflammatory eye diseases such as glaucoma.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.