Methods and composition for a binding molecule targeting cancer cells expressing SSX2 peptide 41-49 in HLA-A*0201 context

US12227590B2 · kind B2 · utility

Assignees

• CHILDREN'S NATIONAL MEDICAL CENTER · US
• The George Washington University · US
• UNIVERSITAT DES SAARLANDES · DE

Inventors

• Eric YVON · Bethesda, US
• Catherine BOLLARD · Bethesda, US
• Stacey Van Pelt · Houston, US
• Scott Raskin · Silver Spring, US
• Gerhard Held · Bürstadt, DE
• Christine Sturm · Homburg, DE
• Michael Pfreundschuh · Homburg, DE

Key dates

• Filing date: Dec 16, 2021
• Grant date: Feb 18, 2025
• Expiry date: Mar 5, 2043

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/33
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are Synovial Sarcoma X breakpoint 2 binding molecules and methods for their use in the detection and treatment of cancer.