Patent · US Active

Recombinase polymerase amplification

US12227773B2 · kind B2 · utility

0Cited by
59References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 23, 2022
Grant dateFeb 18, 2025
Priority date
Expiry dateMay 23, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y207/07
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention features novel, diverse, hybrid and engineered recombinase enzymes, and the utility of such proteins with associated recombination factors for carrying out DNA amplification assays. The present invention also features different recombinase ‘systems’ having distinct biochemical activities in DNA amplification assays, and differing requirements for loading factors, single-stranded DNA binding proteins (SSBs), and the quantity of crowding agent employed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.