Recombinase polymerase amplification
US12227773B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 23, 2022 |
| Grant date | Feb 18, 2025 |
| Priority date | — |
| Expiry date | May 23, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/07
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention features novel, diverse, hybrid and engineered recombinase enzymes, and the utility of such proteins with associated recombination factors for carrying out DNA amplification assays. The present invention also features different recombinase ‘systems’ having distinct biochemical activities in DNA amplification assays, and differing requirements for loading factors, single-stranded DNA binding proteins (SSBs), and the quantity of crowding agent employed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.