Modified template-independent DNA polymerase
US12227775B2 · kind B2 · utility
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31Claims
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Key dates
| Filing date | May 22, 2018 |
| Grant date | Feb 18, 2025 |
| Priority date | — |
| Expiry date | Sep 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/07031
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Described herein are genetically engineered template-independent DNA polymerases, specifically terminal deoxynucleotidyl transferases, and methods of using these polymerases to control DNA synthesis by adding a single nucleotide (mononucleotide) at a time to the 3′ end of a growing single-stranded DNA polynucleotide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.