Patent · US Active

Method for external sterilization of drug delivery device

US12233177B2 · kind B2 · utility

0Cited by

92References

24Claims

0Family size

Assignee

AMGEN INC. · US

Inventors

Wael Mismar · Redondo Beach, US
Jessica Hai Liu · Craydon Court, US
Chia-Jung Wu · Hsinchu, TW
Shermeen A. Abbas · Deer Lake Highlands, US
Shaun Devitt · Wayne, US
Kenneth G. Schalhoub · Denver, US
Anthony Bitong · Calabasas, US
Mads Schjoth Due · Redondo Beach, US
Malak Guirguis · Los Angeles, US
Rami Saifan · Thousand Oaks, US

Key dates

Filing date	Sep 16, 2020
Grant date	Feb 25, 2025
Priority date	—
Expiry date	May 26, 2042

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61M2207/00
WIPO fieldMedical technology
WIPO sectorInstruments

Abstract

A method of externally sterilizing a drug delivery device utilizing Nitrogen Dioxide (NO2) is provided, including placing the drug delivery device in a sterilization chamber, introducing into the chamber a dose of NO2 having a concentration of between about 2 and 20 milligrams per Liter by applying a vacuum level of between about 10 and 600 Torr and holding the vacuum level for a dwell time of between about 2 and 20 minutes, repeating the step of introducing into the chamber a dose of NO2 for a number of pulses between about 1 and 24, purging the sterilization chamber of at least substantially all of the NO2, and aerating the sterilization chamber.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.