Identification of mutations in channelopsin variants having improved light sensitivity and methods of use thereof
US12234267B2 · kind B2 · utility
0Cited by
5References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 19, 2021 |
| Grant date | Feb 25, 2025 |
| Priority date | — |
| Expiry date | Feb 5, 2043 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compositions and kits including at least one nucleic acid or polypeptide molecule encoding for a mutant CoChop protein. Methods of the invention include administering a composition comprising a mutant CoChop to a subject to preserve, improve, or restore phototransduction. Preferably, the compositions and methods of the invention are provided to a subject having impaired vision, thereby restoring vision to normal levels.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.