Peptide construct having a protease-cleavable linker
US12234279B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Mar 9, 2021 |
| Grant date | Feb 25, 2025 |
| Priority date | — |
| Expiry date | Feb 26, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided inter alia a construct suitable for oral administration comprising a first polypeptide and a second polypeptide connected by a labile peptide linker, wherein the labile peptide linker is labile to one or more proteases present in the intestinal tract and wherein the first and second polypeptides are substantially resistant to said one or more proteases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.