Culture medium for expanding and culturing human liver progenitor cells and application thereof
US12234482B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 19, 2019 |
| Grant date | Feb 25, 2025 |
| Priority date | — |
| Expiry date | Apr 1, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5067
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are a culture medium for expanding and cultivating human liver progenitor cells and an application thereof. The chemical components of the formula of the described culture medium are clear, no serum is present, and various components thereof cooperate with each other to synergize. The culture medium is used for the long-term expansion and cultivation of liver progenitor cells in vitro and is used for maintaining the dryness thereof, is beneficial in quickly and efficiently obtaining a large number of functional liver cells, and is suitable for clinical hepatocyte transplantation application as well as for the use of hepatocyte reactors in bioartificial livers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.