Sample injection with fluidic connection between fluid drive unit and sample accommodation volume

US12235248B2 · kind B2 · utility

Assignee

• AGILENT TECHNOLOGIES, INC. · US

Inventors

• Daniel Thielsch · Neuenbürg, DE
• Thomas Ortmann · Ittersbach, DE
• Sam Wouters · Schiftung, DE

Key dates

• Filing date: Sep 18, 2023
• Grant date: Feb 25, 2025
• Expiry date: Sep 18, 2043

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/328
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

An injector, for injecting a fluidic sample into a flow path between a fluid drive and a sample separation unit, includes a sample accommodation volume, a sample drive, and a fluidic valve switchable to selectively couple the volume with the flow path or decouple the volume from the flow path. In an injection switching state, the fluid drive, the separation unit and the sample drive are coupled by the valve so that fluid driven by the sample drive and flowing from the volume to the separation unit and further fluid driven by the fluid drive and flowing from the fluid drive to the separation unit are combined at a fluidic connection upstream of the separation unit. A control unit controls an outlet flow rate value according to which a combination of the mobile phase and the fluidic sample is driven through the separation unit.