Treatment of hearing loss
US12239651B2 · kind B2 · utility
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14References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 19, 2024 |
| Grant date | Mar 4, 2025 |
| Priority date | — |
| Expiry date | Mar 19, 2044 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.