Patent · US Active

Process and apparatus for sequential synthesis of biological polymers

US12239950B2 · kind B2 · utility

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19Claims
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Assignee

Inventor

Key dates

Filing dateApr 9, 2020
Grant dateMar 4, 2025
Priority date
Expiry dateApr 5, 2042

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/582
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A method and apparatus for nucleic acid synthesis. The method employs a device including at least one deprotection unit to carry out a step of deprotection, at least one coupling unit to carry out a step of coupling, at least one oxidation/thiolation unit to carry out a step of oxidation or thiolation, at least one capping unit to carry out a step of capping, and at least one washing unit to carry out a step of washing. A plurality of reaction vessels for nucleic acid synthesis are moved to the units in accord with a synthesis scheme for a desired nucleic acid sequence and at least two reaction vessels are simultaneously acted upon at several of the units in series.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.