Potent and selective human neuronal nitric oxide synthase inhibitors
US12240815B2 · kind B2 · utility
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22References
23Claims
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Key dates
| Filing date | Feb 24, 2021 |
| Grant date | Mar 4, 2025 |
| Priority date | — |
| Expiry date | Feb 24, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are 2-aminopyridine derivative compounds for use as inhibitors of nitric oxide synthase (NOS). In particular, the field of the invention relates to 2-aminopyridine derivative compounds for use as inhibitors of neuronal nitric oxide synthase (nNOS), which are formulated as pharmaceutical compositions for treating diseases and disorders associated with nNOS such as Alzheimer's, Parkinson's, and Huntington's diseases, and amyotrophic lateral sclerosis, cerebral palsy, stroke/ischemic brain damage, and migraine headaches.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.