Composition comprising aflibercept and a variant thereof, and related methods and uses
US12240888B1 · kind B1 · utility
0Cited by
8References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 30, 2024 |
| Grant date | Mar 4, 2025 |
| Priority date | — |
| Expiry date | May 30, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/976
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a composition comprising aflibercept and a variant thereof, wherein the variant is a truncation variant with a truncated VEGF binding portion of aflibercept, and wherein the content of the truncation variant is less than or equal to about 20% by mass percentage. Also provided is a pharmaceutical formulation comprising the composition. Further, provided are a method for detecting the variant and use of the variant in quality inspection or quality control of an aflibercept-containing product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.