Patent · US Active

Method of making exosomes from tumor cell/antigen presenting cell hybrid cells

US12241091B2 · kind B2 · utility

0Cited by

0References

3Claims

0Family size

Assignee

INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Guanghui Ma · Beijing, CN
Wei Wei · Galveston, US
Shuang Wang · Qingdao, CN
Shuang Qing · Beijing, CN
Jianghua Wang · 安丰镇, CN

Key dates

Filing date	Aug 16, 2019
Grant date	Mar 4, 2025
Priority date	—
Expiry date	Jun 14, 2042

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/572
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided is an exosome, which is secreted by a hybrid cell formed by antigen-presenting cells phagocytosing the cell nuclei of tumor cells. Using the strategy of macrophages phagocytosing the cell nuclei of tumor cells achieves endogenous expression of tumor antigens on macrophages, and the exosome prepared has good capabilities of targeting to lymph nodes and tumors dually.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.