Probes for detection of copper

US12241902B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Christopher J. Chang · Berkeley, US
• Yik Sham Clive Chung · Sha Tin, CN
• Sumin Lee · Seoul, KR

Key dates

• Filing date: Apr 29, 2020
• Grant date: Mar 4, 2025
• Expiry date: Jul 22, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure provides Forster resonance energy transfer (FRET)-based probes for detecting copper, e.g., for detecting Cu(I) in live cells. The present disclosure provides methods for detecting copper, e.g., for detecting Cu(I) in live cells, using a FRET-based probe of the present disclosure.