Vitamin K2 microcapsule, preparation method thereof and use thereof in manufacture of medicament for preventing or treating cardiovascular and cerebrovascular diseases
US12245993B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 28, 2020 |
| Grant date | Mar 11, 2025 |
| Priority date | — |
| Expiry date | Dec 20, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure pertains to the technical field of vitamin K2, and relates to a vitamin K2 microcapsule, a preparation method thereof, and use thereof in the manufacture of a medicament for preventing and treating cardiovascular and cerebrovascular diseases. The vitamin K2 microcapsule contains the following components by weight: 0.001 to 10 parts of vitamin K2, 5 to 30 parts of polyunsaturated fatty acid source, 0.1 to 10 parts of vitamin E-polyethylene glycol succinate, 50 to 95 parts of water-phase wall material and 0.01 to 10 parts of antioxidant, the polyunsaturated fatty acid source contains an ω-6 source and an ω-3 source, and the antioxidant is a water-phase antioxidant and/or an oil-phase antioxidant. The vitamin K2 microcapsule prepared by the method of the present disclosure has good water solubility, good stability and high bioavailability, can significantly improve the preventive and/or therapeutic effects on cardiovascular and cerebrovascular diseases, and has broad application prospects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.