Lipid-controlled release compositions

US12246055B2 · kind B2 · utility

Assignee

• CAMURUS AB · SE

Inventors

• Fredrik Tiberg · Lund, SE
• Catalin Nistor · Lund, SE
• Markus Johnsson · Lund, SE
• David Hemmerlin · Basel, CH
• Johannes Franz Kluge · Basel, CH
• Priyanga Wickramanayake · Basel, CH

Key dates

• Filing date: May 29, 2020
• Grant date: Mar 11, 2025
• Expiry date: Jan 3, 2042

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2205/0222
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides a glass syringe or a glass cartridge, for parenterally administering, containing a lipid-based pre-formulation suitable for refrigerated storage, wherein the lipid-based pre-formulation includes 20-80 wt % of a diacyl glycerol having a fatty acid composition of at least 98% oleic acid (18:1), as determined in accordance with method C, 2.4.22 (Composition of fatty acids by gas chromatography), European Pharmacopoeia 9.0; 20-80 wt % of a phospholipid; 1-30 wt % of a solvent; and a bioactive agent.