Synthetic multidomain peptide biomaterials that inhibit inducible nitric oxide synthase
US12251449B2 · kind B2 · utility
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Key dates
| Filing date | Dec 18, 2020 |
| Grant date | Mar 18, 2025 |
| Priority date | — |
| Expiry date | Dec 15, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/507
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compositions comprising multi domain peptide (MDP) hydrogels where the peptides that constitute the hydrogel have at least one N6-(1-iminoethyl)-lysine side chain. Also provided are hydrogels that further comprise a STING agonist, an immune checkpoint inhibitor, and/or an anti-cancer therapy. Also provided are methods of using such compositions in the treatment of cancer.
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