Lipid nanoparticle formulations
US12251470B2 · kind B2 · utility
0Cited by
28References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 8, 2019 |
| Grant date | Mar 18, 2025 |
| Priority date | — |
| Expiry date | Aug 6, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides certain specific lipid nanoparticles comprising: (a) one or more nucleic acid molecules; (b) cholesterol; (c) DSPC; (d) PEG-C-DMA; and (e) a cationic lipid; and pharmaceutical compositions comprising the lipid nanoparticles. The lipid nanoparticles and pharmaceutical compositions are particularly useful for delivering a nucleic acid such as siRNA or mRNA to a patient (e.g. a human) or to a cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.