Decellularized and demineralized bone matrices and methods for making same
US12251493B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Mar 21, 2021 |
| Grant date | Mar 18, 2025 |
| Priority date | — |
| Expiry date | May 12, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21062
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of making a bone matrix includes exposing a bone tissue to a solution including a surfactant and a protease; treating the bone tissue with an acid solution following exposing the bone tissue; and electrophoretically treating the acid treated bone tissue. A bone matrix has a DNA content of not greater than 0.1 micrograms per milligram sample and a modulus in a range of 180 kPa to 250 kPa.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.