Substrates, systems, and methods for array synthesis and biomolecular analysis
US12251674B2 · kind B2 · utility
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38References
13Claims
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Key dates
| Filing date | Jul 14, 2020 |
| Grant date | Mar 18, 2025 |
| Priority date | — |
| Expiry date | Jul 16, 2043 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00725
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N→C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.