Patent · US Active

Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use

US12252552B2 · kind B2 · utility

0Cited by

47References

32Claims

0Family size

Assignee

Sutro Biopharma, Inc. · US

Inventors

Christopher D. Thanos · Tiburon, US
Leslie McEvoy · Mountain View, US
Gang Yin · South San Francisco, US
Kalyani Penta · Palo Alto, US
Ramesh Baliga · Redwood City, US
Sunil Bajad · Fremont, US
Sonia Pollitt · San Mateo, US
Chris Murray · Soquel, US
Alex Steiner · San Francisco, US
Avinash Gill · Emeryville, US

Key dates

Filing date	Nov 26, 2019
Grant date	Mar 18, 2025
Priority date	—
Expiry date	May 12, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/52
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are modified Fc proteins comprising non-natural amino acid residues at site-specific positions, conjugates of the modified Fc proteins for therapy or diagnosis, compositions comprising the modified Fc proteins and conjugates thereof, methods of their production and methods of their use. The modified Fc proteins and conjugates are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.