Use of engineered liver tissue constructs for modeling liver disorders
US12252712B2 · kind B2 · utility
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13References
15Claims
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Key dates
| Filing date | Apr 3, 2018 |
| Grant date | Mar 18, 2025 |
| Priority date | — |
| Expiry date | Jun 30, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention is directed to three-dimensional, engineered, bioprinted biological tissue constructs exhibiting a liver disorder, methods of making the constructs, and use of the constructs in assays, such as drug testing and molecular diagnostic testing, including methods of assessing the ability of a candidate therapeutic agent to reverse, reduce, or prevent a liver disorder, and methods for biomarker discovery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.