Systems and methods for improved light-sheet microscopy
US12253469B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 16, 2020 |
| Grant date | Mar 18, 2025 |
| Priority date | — |
| Expiry date | Sep 15, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/0621
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein are systems and methods for improving light-sheet microscopy with cost-effective and simplified components. Such cost-effective and simplified components can be implemented in a light focusing system, a light generation system, and/or in imaging system. The light focusing system can be improved by attaching a voice coil motor to a focusing lens to increase the imagable field of view. The light generation system can be improved with a multimode laser diode to increase the uniformity of the beam profile and to increase the usable optical power. The imaging system can be improved by using a fluid chamber with positive cylindrical optical window for minimizing spherical aberrations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.