Identification, characterization, and quantitation of CRISPR-introduced double-stranded DNA break repairs
US12254959B2 · kind B2 · utility
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Key dates
| Filing date | Jul 2, 2020 |
| Grant date | Mar 18, 2025 |
| Priority date | — |
| Expiry date | Sep 23, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B40/20
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Described herein is a system and process for identifying and characterizing double-stranded DNA break repair sites that are based on biological information and have improved accuracy. Also described is a sequence alignment process that uses biological data to inform the alignment matrix for position specific alignment scoring, resulting in the identification of noncanonical target sites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.