Minimizing aeration of suspensions during in-line mixing
US12257351B2 · kind B2 · utility
0Cited by
15References
11Claims
0Family size
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Key dates
| Filing date | Feb 21, 2020 |
| Grant date | Mar 25, 2025 |
| Priority date | — |
| Expiry date | Feb 21, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods of making a pharmaceutical composition comprising: providing a matrix solution/suspension comprising a matrix former, a structure former, 0.1-1.5 wt. % anti-aerating agent, and a solvent; mixing a plurality of hydrophobic particles into the matrix solution/suspension to form a pharmaceutical suspension; and dosing the pharmaceutical suspension into preformed blister packs, wherein a dosed weight of the dosed pharmaceutical suspension is within 10 % of a target dosed weight.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.