Preparation of seimicarbazide-sensitive amine oxidase inhibitor and use thereof

US12258336B2 · kind B2 · utility

Assignee

• SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. · CN

Inventors

• Shengyang LIU · Shanghai, CN
• Jianwen DENG · Shanghai, CN
• Zhiyong FENG · Shanghai, CN
• Lei Jiang · Shanghai, CN
• Zhi Qiao · Shanghai, CN
• Ke Shang · Beijing, CN
• Xiaoping XIE · Shanghai, CN
• Xueli Xu · Plainsboro, US
• Yuan Xu · Singapore, SG
• Haixia ZHAO · Shanghai, CN

Key dates

• Filing date: Sep 25, 2019
• Grant date: Mar 25, 2025
• Expiry date: Feb 5, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/107
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided are a preparation of semicarbazide-sensitive amine oxidase inhibitor and the use thereof. In particular, disclosed are a compound as shown in formula I, or a stereoisomer or racemate or pharmaceutically acceptable salt thereof. Also disclosed is that the above-mentioned compound can inhibit semicarbazide-sensitive amine oxidase.